|
KMID : 1059519960400030173
|
|
Journal of the Korean Chemical Society
1996 Volume.40 No. 3 p.173 ~ p.179
|
|
|
Observation of Effects of Phosphatidylcholine and Al Salts Concentration on the Formation of Vesicles by TEM
|
|
Chung Jong-Jae
Kim Chang-Hyun
Lee Byung-Kyo
Lee Hae-Wook
|
|
|
Abstract
|
|
|
|
Transmission Electron Microscopy (TEM) was used to monitor the response of vesicle size and the intervesicle agglomeration with a variety of experimental parameters. Considered parameters are: (a) reaction temperture, (b) concentration of phosphatidylcholine, (c) concentration of aluminum ion with fixed concentration of phosphatidylcholine at 0.39 mM, and (d) mixed concentration of aluminum and phosphatidylcholine when fixing the weight ratio of phosphatidylcholine to aluminum at 0.01. Controlling these parameters, vesicle size changed and intervesicle agglomeration observed. As reaction temperature and the concentration of phosphatidylcholine increase, vesicle size decreases. With 0.2 M of aluminum ion, abnormal vesicle growth led by intervesicle agglomeration and coalescence was observed. When weight ratio of phosphatidylcholine to aluminum is 0.01, optimal vesicle size and size distribution can be obtained.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|